ChIP-chip

Roche NimbleGen provides the most sensitive ChIP-chip (chromatin immunoprecipitation on chip) microarrays on the market. These arrays enable rapid identification of precise binding sites of specific DNA-binding proteins—such as transcription factors, histones, and polymerases—within a target genome, as well as uncover chromatin remodeling in any region of a genome. NimbleGen ChIP-chip microarrays and services have become the platform of choice supported by an ever-growing list of peer-reviewed publications.

Coupled with chromatin immunoprecipitation, the service offers:

• Precise identification of DNA binding sites or chromatin structure across whole genomes or within biologically focused regions including promoters.
• Highly sensitive detection of DNA binding sites due to the use of long (50-75mer), isothermal oligonucleotide probes.
• Comprehensive catalog collection of targeted promoter and Deluxe Promoter array designs as well as whole-genome tiling arrays for multiple organisms.