NimbleGen DNA Array Service

Genotyping

Roche NimbleGen offers ultra-high resolution CGH/CNV arrays with up to 2.1 million probes for comprehensive analysis of DNA copy number variation. In addition to the 2.1M array format, multiplex arrays are available for higher throughput and cost-effective analysis of either 3 or 12 samples on a single slide. Roche NimbleGen offers several types of CGH/CNV arrays for a variety of organisms to meet your specific research needs.

ChIP-chip

The combination of chromatin immunoprecipitation (ChIP) and high resolution tiling arrays is a powerful approach to identify transcription factor binding sites or chromatin modifications. Successful ChIP depends on numerous factors, such as antibody binding and crosslinking, or chromatin shearing, which often requires thorough optimization. Thus, we offer ChIP-on-Chip as a core service, starting from enriched and amplified DNA after immunoprecipitation. Roche NimbleGen provides the most sensitive ChIP-chip (chromatin immunoprecipitation on chip) microarrays and services on the market. These arrays enable rapid identification of precise binding sites of specific DNA-binding proteins—such as transcription factors, histones, and polymerases—within a target genome, as well as uncover chromatin remodeling in any region of a genome. NimbleGen ChIP-chip microarrays have become the platform of choice supported by an ever-growing list of peer-reviewed publications.